studies

Using PCORnet to Expand the DS-CONNECT Cohort Through Healthcare System Recruitment, Incorporating Electronic Health Records, and Assessing Self-Determination (DS-DETERMINED)

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Introduction

This study seeks to support and enhance Down syndrome research capabilities via the DS-CONNECT registry by leveraging PCORnet, the National Patient-Centered Clinical Research Network.

Principal Investigators

Colombo, John, PhD

About

Since 2014, the Patient-Centered Research Institute’s investment in creating PCORnet has resulted in a diverse national network covering over 100 millon lives: providing curated, electronic health record data and claims as real world evidence along with heightened patient/clinician/health system engagement across participating organizations. We will link PCORnet to DS-CONNECT and test capability in three dimensions: 1) increasing DS-CONNECT registry enrollment, 2) extracting clinical observations, treatments, and outcomes from PCORnet for DS-CONNECT patients, and 3) conducting cognitive assessment via DS-CONNECT in the PCORnet population. People with Down syndrome and intellectual and developmental disabilities experience poorer health-related quality of life than people without a disability.