Generation of isogenic trisomy 21 iPSC resource

Bhattacharyya, AnitaJackson Cook, Colleen K


As the most common genetic cause of intellectual disability, Down syndrome is a public health concern. The proposed research will create new models of Down syndrome to advance the study of Down syndrome neuropathophysiology. The aims of this proposal include generating Down syndrome-specific human pluripotent stem cells from non-embryonic sources.

Down Syndrome Publications

American journal on intellectual and developmental disabilities2020