Abman, Steven Herbert MD

INCLUDE Grants​

Academic Training in Cardiopulmonary Disease in Down Syndrome

Abman, Steven Herbert

The overall goal of the program is to increase the number of highly trained basic and physician-scientists who can successfully develop sustainable careers in academic medicine. Under teams of talented co-mentors, the program will establish unique programs that will enable young investigators to develop long-lasting skills and to perform high level laboratory and/or clinical-translational research, which will ultimately improve our understanding of the pathobiology of lung and heart diseases associated with DS, enable the design of therapeutic strategies that will ultimately improve both short and long-term respiratory outcomes associated with DS.

Data Fusion: A Sustainable, Scalable, Open Source Registry Advancing PVD Research

Abman, Steven HerbertMandl, Kenneth D

Pediatric pulmonary vascular disease (PVD), including pediatric pulmonary hypertension, although relatively rare in childhood, exacts a disproportionately high social and economic burden on the children and their families faced with this illness, as well as society as a whole. Yet, treatment options are limited and despite new drug therapies, survival of patients with severe PVD remains poor. We therefore establish a Bioinformatics Clinical Coordinating Center, comprised of experts and centers in pulmonology, cardiology, and bioinformatics, which will collect data on the largest research population of children with this disease to-date, and analyze both registry and electronic health record data in novel ways so that we may better address the many unanswered questions of PVD in children. (End of Abstract)

Down Syndrome Publications​