fNIRS as an outcome measure of the prefrontal hemodynamic response in Down syndrome

Ayaz, HasanEdgin, Jamie OLee, Nancy Raitano

(Relevance): The proposed research aims to test the use of a patient-friendly neuroimaging technology called functional near infrared spectroscopy (fNIRS) with children with Down syndrome to determine if it can be used to measure the efficacy of treatments aimed at improving cognition and sleep in this group. This research also seeks to understand how sleep influences brain function in children with Down syndrome and those with typical development. Thus, the proposed research has implications for informing efforts to improve health and well- being for individuals with Down syndrome and those in the general population with sleep disturbance.