Linsley, Peter S PHD

INCLUDE Grants​

Anti-tumor and autoimmunity signatures in Down syndrome

Buckner, Jane HoytLinsley, Peter S

The proposed research is relevant to public health because it investigates why individuals with Down syndrome are at increased risk for autoimmune disease yet are protected from development of solid tumors. It will advance our understanding of anti-tumor mechanisms and thus provide insight into how to improve cancer immunotherapy. This knowledge will also be important for developing therapeutic approaches to treat autoimmune disease in Down syndrome.