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Noradrenergic dysfunction in Down Syndrome

Ledreux, Aurelie

Summary

Down syndrome (DS) is a genetic condition that occurs in 1 out of 700 births with more than 350,000 Americans affected. Alzheimer's disease (AD) occurs with high penetrance in DS and few treatment options are available. Data obtained from this project can translate to treatment potentials in AD in the general population and are focused on noradrenergic systems and inflammation.

Down Syndrome Publications